Wednesday, May 6, 2020
Types Of Dementia For Cerebral Autosomal Dominant Ateriopathy
Other type of dementia can be coupled with a rare hereditary disorder known as CADASIL which stands for cerebral autosomal dominant ateriopathy with subcortical infarct and leukoencephalopathy. This disorder is linked to abnormalities of a specific gene, Notch3 located on chromosome 19. The first symptoms arise at the age of 20 or 35 or 40 and the individuals often die at the age of 65. Researchers are still working to find out the exact cause of CADASIL. Other causes of vascular dementia include vasculitis, hypertension and lesions caused due to brain hemorrhage. An autoimmune disease, lupus erythematosus and inflammatory disease temporal arteritis can also damage blood vessels resulting in dementia. 3. Lewy body dementia (LBD) Lewyâ⬠¦show more contentâ⬠¦This disorder however lacks amyloid plaques but neurofibrillary tangles are present that disrupt normal activities of cells resulting in their death. Experts believe that fronto-temporal dementia accounts for about 2-10% of all cases of dementia. The symptoms usually appear between the ages of 40 and 65. In some cases, people have a familial history of the disease and in such case genetic factor strongly influences the disease. People with this disorder may live up to 5-10 years after the diagnosis of disease. The frontal and temporal lobes of brain are concerned with judgment and social behavior but in this disorder as the nerve cells are destroyed so the individual finds it difficult to make decisions as well as maintain social communication. Other possible symptoms include loss of speech and language, repetitive behavior, increased appetite and motor problems like stiffness and balance problems. Memory loss occurs in later stages of the disease. Pick s disease is one type of fronto-temporal dementia characterized by abnormal and swollen nerve cells that later die. The brains of individuals suffering from this disorder show presence of abnormal Pick bodies which contain tau protein. Exact cause of Pick s disease is unknown but it is believed that some genes may be associated with it. The symptoms
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